Why do I need this report?

Phase II detox is where your body “neutralizes and packages” compounds so they can be safely eliminated. If your genetics reduce efficiency in key Phase II steps—like glutathione conjugation (GST genes), glucuronidation (UGT genes), acetylation (NAT2), sulfation (SULT1A1), or methylation (COMT/MTHFR)—you may be more reactive to common exposures such as smoke, air pollution, alcohol, certain medications, or endocrine disruptors. This report helps you understand which pathways may need extra support so you can make more targeted, evidence-informed choices instead of relying on generic detox advice.

Why is this report unique?

This report is unique because it combines a focused analysis of 26 Phase II detox and antioxidant-related genetic variants with 10 personalized recommendations you can use immediately. It doesn’t just list genes—it connects your results to practical next steps across major Phase II mechanisms (glucuronidation, glutathione activity, sulfation, acetylation, methylation) and related DNA repair support, translating complex genetics into a clear action plan.

How is the recommendations list built?

Your recommendations list is built by weighting each genetic finding based on (1) predicted functional impact (how strongly a variant may influence enzyme activity or regulation), (2) pathway relevance to Phase II detox (e.g., glutathione, UGT, GST, NAT, SULT, methylation/NRF2 signaling), and (3) the quality and consistency of scientific evidence linking variants to detox-related outcomes or sensitivities. The final list prioritizes the highest-impact, most actionable areas first, then adds supportive dietary and supplement options aligned with your overall pathway pattern.

What is Phase II detoxification and why does glutathione matter?

Phase II detoxification is the set of biochemical “conjugation” reactions that make potentially harmful compounds easier to remove from the body—often by making them more water-soluble. Key Phase II routes include glucuronidation (UGT enzymes), glutathione conjugation (GST enzymes), sulfation (SULT enzymes), acetylation (NAT enzymes), and methylation (methyltransferases, supported by genes like COMT and MTHFR). Glutathione is often called the body’s “master antioxidant” because it helps neutralize reactive compounds and supports detox enzymes that bind toxins for elimination. Genetic variants in glutathione-related genes (such as GSTP1, GCLC, GSTA1, and GPX1) may influence how effectively your body handles certain exposures, including pollutants, smoke, heavy metals, and oxidative stress—making personalized support strategies especially valuable.

Which genes are included in a Phase II Detox DNA report?

A Phase II Detox DNA report typically focuses on genes involved in conjugation and antioxidant regulation, including UGT genes (e.g., UGT1A1, UGT2A1) for glucuronidation; GST genes (e.g., GSTP1 and related glutathione-pathway genes such as GCLC, GSTA1, GPX1) for glutathione-based detox; NAT2 for acetylation status (including “slow acetylator” patterns); SULT1A1 for sulfation; and regulatory genes like NFE2L2 (NRF2 signaling) that can influence broad antioxidant and detox gene activation. Many reports also include DNA repair genes such as XPC, XRCC1, and XRCC4, which are relevant to how the body responds to damage associated with exposures like air pollution, pesticides, and mold. This report analyzes 26 variants across these pathways to generate a personalized, actionable plan.

Save $30

Phase II Detox

Rated 4.67 out of 5 based on 12 customer ratings

4.7 (13 reviews)

Phase II Detox

Rated 4.67 out of 5 based on 12 customer ratings

4.7 (13 reviews)

The report provides up to 10 personalized recommendations based on over 26 genetic variants analyzed. Purchase a DNA kit to generate your genetic results. If you've already got one, you're all set to continue. View sample report.

$59

$29

Save $30

Add to cart Added

Trusted by 200,000+ users & 2,000+ doctors

Proven track record: 3+ million analyses delivered

Analyzes 26 Genetic Variants

Up to 10 DNA-Based, Science-Backed Recommendations

Phase II Detox

$59 $29

Add to cart Added

Product features

Note: To generate your personalized report, purchase a SelfDecode DNA kit. If you already have one, you’re ready to proceed.

Understanding Your Phase II Detox Risks: A DNA-Based Report

Do you ever feel unusually sensitive to smoke, air pollution, alcohol, or certain chemicals—even when others seem fine? Wondering why “detox” strategies work for some people but not for you? If you’re dealing with fatigue, brain fog, or stubborn reactions to everyday exposures, your Phase II detox pathways—especially glutathione and methylation—may be a key piece of the puzzle.

Key Report Highlights

The Phase II Detox DNA Report analyzes 26 clinically relevant genetic variants (SNPs) across core Phase II detox and antioxidant pathways to show how your body may neutralize and clear toxins after Phase I processing. You’ll receive 10 personalized, actionable recommendations tailored to your results. Why Phase II matters: many compounds must be “tagged” through processes like glucuronidation, sulfation, glutathione conjugation, acetylation, and methylation to become water-soluble—so they can be safely eliminated rather than recirculating in the body.

Personalized, Actionable Recommendations

Your recommendations are personalized to the specific detox enzymes and regulatory genes where your genetics may shift function (for example, pathways involving UGTs for glucuronidation, GST enzymes that use glutathione, and methylation-related genes such as COMT and MTHFR). Recommendations include targeted dietary and supplement guidance designed to support your body’s natural clearance processes. Examples of what may appear in your plan include food strategies to support glutathione status (e.g., emphasizing sulfur-containing and antioxidant-rich foods) and supplement options commonly used to support Phase II pathways (e.g., glutathione-support nutrients or methylation cofactors), selected based on your genetic profile and the strength of evidence.

User-Friendly Format and Trust

The user-friendly format of this report emphasizes clarity, offering practical, easy-to-follow insights to integrate seamlessly into your lifestyle. Whether you’re a novice or seasoned biohacker, you’ll find the layout accessible and the information straightforward.

This report is grounded in the latest scientific research and trusted by over 150,000 users and 1,000+ doctors worldwide. It’s not only comprehensive but also complies with stringent privacy laws, being HIPAA and GDPR compliant.

Getting Started

Ready to unlock the secrets within your DNA? Purchase a DNA kit for an easy at-home collection process and gain the insights you need for a proactive, personalized approach to wellness. Don’t wait—take the first step to understanding your health today.

Product FAQs

: Phase II detox is where your body “neutralizes and packages” compounds so they can be safely eliminated. If your genetics reduce efficiency in key Phase II steps—like glutathione conjugation (GST genes), glucuronidation (UGT genes), acetylation (NAT2), sulfation (SULT1A1), or methylation (COMT/MTHFR)—you may be more reactive to common exposures such as smoke, air pollution, alcohol, certain medications, or endocrine disruptors. This report helps you understand which pathways may need extra support so you can make more targeted, evidence-informed choices instead of relying on generic detox advice.
: This report is unique because it combines a focused analysis of 26 Phase II detox and antioxidant-related genetic variants with 10 personalized recommendations you can use immediately. It doesn’t just list genes—it connects your results to practical next steps across major Phase II mechanisms (glucuronidation, glutathione activity, sulfation, acetylation, methylation) and related DNA repair support, translating complex genetics into a clear action plan.
: Your recommendations list is built by weighting each genetic finding based on (1) predicted functional impact (how strongly a variant may influence enzyme activity or regulation), (2) pathway relevance to Phase II detox (e.g., glutathione, UGT, GST, NAT, SULT, methylation/NRF2 signaling), and (3) the quality and consistency of scientific evidence linking variants to detox-related outcomes or sensitivities. The final list prioritizes the highest-impact, most actionable areas first, then adds supportive dietary and supplement options aligned with your overall pathway pattern.
: Phase II detoxification is the set of biochemical “conjugation” reactions that make potentially harmful compounds easier to remove from the body—often by making them more water-soluble. Key Phase II routes include glucuronidation (UGT enzymes), glutathione conjugation (GST enzymes), sulfation (SULT enzymes), acetylation (NAT enzymes), and methylation (methyltransferases, supported by genes like COMT and MTHFR). Glutathione is often called the body’s “master antioxidant” because it helps neutralize reactive compounds and supports detox enzymes that bind toxins for elimination. Genetic variants in glutathione-related genes (such as GSTP1, GCLC, GSTA1, and GPX1) may influence how effectively your body handles certain exposures, including pollutants, smoke, heavy metals, and oxidative stress—making personalized support strategies especially valuable.
: A Phase II Detox DNA report typically focuses on genes involved in conjugation and antioxidant regulation, including UGT genes (e.g., UGT1A1, UGT2A1) for glucuronidation; GST genes (e.g., GSTP1 and related glutathione-pathway genes such as GCLC, GSTA1, GPX1) for glutathione-based detox; NAT2 for acetylation status (including “slow acetylator” patterns); SULT1A1 for sulfation; and regulatory genes like NFE2L2 (NRF2 signaling) that can influence broad antioxidant and detox gene activation. Many reports also include DNA repair genes such as XPC, XRCC1, and XRCC4, which are relevant to how the body responds to damage associated with exposures like air pollution, pesticides, and mold. This report analyzes 26 variants across these pathways to generate a personalized, actionable plan.

WHY SELFDECODE?

Empowering Your Well-being Journey

This personalized health report is powered by SelfDecode's cutting-edge AI technology, designed to unlock a deeper understanding of your health potential. We're committed to providing you with the most accurate and actionable insights to guide your well-being journey.

Most Accurate
Polygenic Risk Scoring

We leverage cutting-edge algorithms and analyze a massive dataset of 2 million people to deliver the most precise assessment of your genetic health predispositions. Our advanced approach takes into account your ancestry - which is often overlooked by other methods - to provide you with the most accurate risk assessment. This ensures that the risk scores you receive are based on the latest scientific evidence and are truly personalized to your genetic makeup.

Cutting-Edge AI &
Machine Learning

We have invested 20 million dollars developing our AI and machine learning models. Our patent-pending technology provides you with the most personalized health insights and recommendations by taking into account your unique DNA, lifestyle, labs, symptoms, conditions and health goals. This empowers you to make informed decisions tailored to your specific needs.

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

We go beyond the basics by analyzing a staggering 200 million genetic variants to provide the most comprehensive picture of your health potential. Our sophisticated recommendation engine leverages this deep analysis to provide personalized and actionable insights to optimize your well-being journey.

Built by Leading
Scientists & Engineers

A dedicated team of over 60 scientists and engineers is continuously innovating and developing our technology, ensuring it remains at the forefront of personalized health.

Reviews

Rated 4.67 out of 5 based on 12 customer ratings

4.7 (13 reviews)

Share your thoughts

If you've used this product, share your thoughts with other customers

Only customers who purchased this product can leave reviews

Rebecca A.

Rated 3 out of 5
Interesting genetics, but the supplement section felt salesy, and I worried about stacking NAC with other meds without clearer cautions.
Jayden S.

Rated 4 out of 5
Clear detox pathways, and the SOD and glutathione suggestions were practical. I just wanted a simple weekly schedule included.
Hannah B.

Rated 5 out of 5
Elimination diet, fewer flareups.
Tyler S.

Rated 5 out of 5
NAC pick stopped my crashes.
Melissa Z.

Rated 5 out of 5
I was pretty skeptical about DNA health stuff at first, but this actually felt useful. Once I got my results with tailored supplement and diet tips, it clicked for me. It wasn’t hype or fluff, there were some actionable things I could start trying right away. Glad I gave it a shot.

1 2 3

Phase II Detox

Product features

Understanding Your Phase II Detox Risks: A DNA-Based Report

Key Report Highlights

Personalized, Actionable Recommendations

User-Friendly Format and Trust

Getting Started

Product FAQs

Why do I need this report?

Why is this report unique?

How is the recommendations list built?

What is Phase II detoxification and why does glutathione matter?

Which genes are included in a Phase II Detox DNA report?

WHY SELFDECODE?

Empowering Your Well-being Journey

Most AccuratePolygenic Risk Scoring

Cutting-Edge AI &Machine Learning

Analyzes 200 Million Variants & Sophisticated Recommendation Engine

Built by Leading Scientists & Engineers

Reviews

Related Products

Most Accurate
Polygenic Risk Scoring

Cutting-Edge AI &
Machine Learning

Built by Leading
Scientists & Engineers