Your genetics plays a key role in your health. The millions of variants you have establish a starting point of strengths and weaknesses for every part of your health, wellbeing, and personality .
You can’t know, utilize, and mitigate against all of these, so it’s crucial to understand core genetic factors that make a difference . Decoding your genetics and using the information to optimize your health regimen is what you are here for, and this report is a great starting point !
Keep in mind that your genetics is just one piece of the puzzle . It combines with all of the other factors in your life from diet and lifestyle to current health conditions to create an overall predisposition to any given health condition or trait.
For example, your genetics might be making you highly susceptible to a health condition, but because you eat well, exercise regularly, don’t smoke, etc... your overall risk can be quite low . The opposite can hold true as well, when poor choices in diet and lifestyle amplify your genetic predisposition and make you far more likely to develop a health condition.
While it goes without saying that living a healthy life in general will mitigate the majority of genetic risks, there are things that require special attention due to your unique genetics and circumstances . This is our goal here. We want to help you find personalized options that make you the best version of yourself.
We have conveniently grouped together our health reports into major topics, like Brain Health or Gut Health, which you will find below. This will give you an overview of your genetic strengths and weaknesses and help guide you into more detailed looks at particular topics.
Our summary reports will then give you a more detailed examination of your genetics in a certain topic and give you additional reports to examine closer. These deep dives will give you a genetic score, specific recommendations you can follow, lifestyle factors to consider, and potential lab markers to help monitor your health.
Get started and dive in! The path toward decoding your genes and optimizing your health awaits!
Continue to the recommendations tab for more details.
About 1 in 4 people in the US have a diagnosable mental disorder. We all face hardships, but why do certain people cope better than others? Genetics has a major impact on how we cope with mental challenges . That’s why our minds are so unique, even when faced with similar conditions.
Your genetic predispositions can impact your brain’s ability to adapt, cope, and function well, influencing your susceptibility to everything from stress to mood problems or brain fog .
Check out the brain health category to discover your genetic predispositions, and find out what positive actions you can take to optimize your brain health!
Up to 65% of the differences in people's anxiety rates may be due to genetics.
Genetic factors account for roughly 40% of differences in depression.
Up to 45% of differences in the way we perceive stress may be due to genetics.
Your genetics has a major impact on brain fog and may help indicate its triggers.
Heart disease is the leading cause of death worldwide . In the Western world, artery hardening or atherosclerosis is the underlying cause of about 50% of all deaths! One of the reasons is that heart disease typically doesn’t have symptoms until a significant event occurs, like a stroke or heart attack.
On the bright side, a third of deaths related to heart disease could be prevented ! Because heart disease is impacted by so many variables, it should come as no surprise that your genetics has a major impact on heart health and your ability to take preventive action.
Open this section to learn more about this complex interplay of genetic and lifestyle factors and check your results!
Genetics may account for up to 50% of differences in blood pressure.
Up to 40% of differences in people's heart disease rates may be due to genetics.
Genetics may account for up to 65% of differences in cholesterol levels.
Genetics may account for about 60% of differences in artery hardening.
Your gut health is a lot more than just healthy digestion! It is a central hub of health in your body, comprising about 70% of your immune system and having a direct connection to your brain.
Genetics can affect every aspect of gut health, including food digestion, gut inflammation, and the gut-brain axis. This report will go through your genetic predispositions
to gut conditions like IBD, IBS, or gluten intolerance
, and reveal the best ways to approach gut health based on your DNA.
Up to 75% of differences in people’s IBD rates may be due to genetics.
Genetics accounts for up to 60% of differences in people’s IBS rates.
You and a friend eat roughly the same diet, walk for 20 minutes each day, and get about the same amount of sleep, yet they are borderline diabetic and you are not. A recent study indicated that only about 1 in 8 people in the U.S. have optimal metabolic health.
Your metabolic health is about much more than weight. It is a system designed to process nutrients for energy, maintain temperature, detox your body, and so much more! If any part of that system gets out of balance, it can mess up the whole thing. This can lead to problems like diabetes, obesity, and underactive thyroid.
Determining your weak points
will allow us to guide you into personalized lifestyle and dietary changes to boost your metabolic health.
Genetics accounts for up to 70% of differences in body weight.
Up to 80% of differences in people's type 2 diabetes rates may be due to genetics.
Genetics accounts for up to 65% of differences in insulin resistance.
Up to 70% of differences in thyroid hormone levels may be due to genetics.
Who doesn’t want to live forever? A lot of potential “Fountains of Youth” have been tried over the years to varying degrees of success. We invest a lot of time and money trying to live longer, but one fact remains: some people live longer than others .
If you’re wondering why that is— meet the genetics of longevity! Your DNA influences your potential to live a longer life. More importantly, it can reveal parts of your health with the biggest impact on your longevity.
With the help of this info, we suggest
tailored dietary and lifestyle changes that will benefit your longevity the most
.
About 10% of differences in people's longevity may be due to genetics.
Hormones are your body’s regulators, telling your organs, tissues, and cells what to do and when to do it. Your genetics definitely has something to say about your susceptibility to hormone issues, as do other factors like diet and lifestyle.
Your recommendations are prioritized according to the likelihood of it having an impact for you based on your genetics, along with the amount of scientific evidence supporting the recommendation.
You’ll likely find common healthy recommendations at the top of the list because they are often the most impactful and most researched.
The Mediterranean diet may lower blood sugar levels in the long run . It’s rich in foods that help reduce inflammation and insulin resistance [ R , R , R , R , R , R ].
People who stick to the Mediterranean diet may thus be less likely to have diabetes. Studies suggest this type of diet may be the best choice for people at risk of diabetes [ R , R , R , R ].
The Mediterranean diet is rich in
olive oil
.
Eating olive oil may lower blood sugar levels and reduce the risk of diabetes
[
R
].
Many behaviors that alter your sleep schedule may have a negative impact on your internal clock. These include:
You can lower your exposure to bright light in the evening by minimizing your screen time. This strategy may improve your sleep duration and quality [R, R, R].
On the other hand, exposure to bright light in the morning may improve your sleep. It helps rebalance your internal clock by boosting the sleep hormone melatonin at night. As a result, it can help you go to bed and wake up earlier [R, R, R, R, R].
Getting a healthy dose of sunlight is the easiest way to get more bright light during the day. Light therapy is also an option [R, R, R, R].
Remember, your genes only tell one important part of your health story!
These next steps will teach you how to get the most complete picture of your health.
Ever heard of the term Nature vs. Nurture?
The truth is, it's both! The assessments below reveal the "nurture" piece of your health story by providing a risk
score based on your lifestyle, environment and medical history. As your life changes, you can re-take the
assessments and watch your risk levels change with it!
What is your age?
Do you drink coffee in the evening several times a week?
In the past year, have you regularly consumed more than 14 alcoholic drinks in a week, or more than 5 drinks in a single day?
Do you often feel anxious?
Do you often experience periods of low mood?
In a typical week, how many times do you participate in any physical activities or exercise for 30 minutes at a time? (such as walking, running, bike riding, weight training, yoga, etc.)
*Note: longer exercise equals more sessions (e.g., 1 hour = 2 sessions)
What is your sex?
Do you currently live alone?
Your lab results are impacted by the combined effect of your genes, environment and lifestyle.
Lab tests will give you the best picture of your current health status, while your genes provide insight into your
health predispositions and which recommendations are best for you.
CRP levels are related to inflammation. Having higher CRP levels can mean that you have more inflammation in your body. People with depression may have increased CRP levels.
CRP levels are related to inflammation. Having higher CRP levels can mean that you have more inflammation in your body. High CRP levels may increase the risk of heart disease in both healthy people and those with artery hardening.
CRP levels are related to inflammation. Having higher CRP levels can mean that you have more inflammation, infections, or other acute issues. High CRP levels are associated with high blood pressure and a higher risk of heart disease.
CRP levels are related to inflammation. Having higher CRP levels can mean that you have more inflammation in your body. People with irritable bowel should be tested for CRP to exclude inflammatory bowel disease.
This test measures hs-CRP, an inflammation marker. Having higher CRP levels can mean that you have more inflammation in your body. Obesity is associated with a higher level of low-grade inflammation reflected by high hs-CRP levels.
This test measures hs-CRP, an inflammation marker. Having higher CRP levels can mean that you have more inflammation in your body. People with high levels of hs-CRP may have an increased risk of diabetes. Diabetic people with high hs-CRP may have a higher risk of heart and kidney complications.
This test measures hs-CRP, an inflammation marker. Having higher CRP levels can mean that you have more inflammation in your body. People with chronic fatigue may have increased hs-CRP levels.
This test measures hs-CRP, an inflammation marker. Having higher CRP levels can mean that you have more inflammation in your body. Chronic pain is associated with higher CRP levels.
This test measures hs-CRP, an inflammation marker. Having higher CRP levels can mean that you have more inflammation in your body. Low levels are associated with chronic medical conditions like obesity and chronic pain, but high levels may be linked to infections or other acute issues.
Anemia is caused by low hemoglobin. Anemia is a common cause of fatigue. If you have low hemoglobin, talk to your doctor about further testing and treatment.
Triglycerides are a kind of bad fat that contributes to your risk of artery hardening. Try to keep your triglyceride levels low with a good diet and a healthy lifestyle
Triglycerides are a kind of bad fat that is linked to heart disease. Try to keep your triglycerides low with exercise and a healthy diet.
Triglycerides are a kind of fat that is linked to heart disease. Try to keep your triglycerides low with exercise and a healthy diet.
Your LDL is your 'bad cholesterol'. Having a high LDL can lead to artery hardening. Try to keep your LDL as low as possible.
Your LDL-cholesterol is your 'bad cholesterol'. People with elevated LDL cholesterol are at greater risk for heart disease. Try to keep your levels as low as possible with diet and exercise.
Your LDL-cholesterol is your 'bad cholesterol'. Having a high LDL-cholesterol can lead to heart disease and other issues. Try to keep your LDL cholesterol as low as possible.
This is the top number of your blood pressure. An elevated blood pressure can raise your risk of artery hardening. If your blood pressure is too high, try to lower it with diet and exercise.
This is the top number of your blood pressure. Having a systolic blood pressure that is too high or too low is not good for your health. Try to keep it in a normal range.
This is the top number of your blood pressure. Having a high blood pressure is linked to heart disease. Try to keep your blood pressure at a normal level with diet and exercise
This is the top number of your blood pressure. People with a high body weight are at risk for high blood pressure. Try to check your blood pressure often to and try to keep it in a healthy range with diet and exercise. This helps prevent other health conditions.
This is the bottom number of your blood pressure. An elevated blood pressure can raise your risk of artery hardening. If your blood pressure is too high, try to lower it with diet and exercise.
This is the bottom number of your blood pressure. Having a diastolic blood pressure that is too high or too low is not good for your health. Try to keep it in a normal range.
This is the bottom number of your blood pressure. Having a high blood pressure is linked to heart disease. Try to keep your blood pressure at a normal level with diet and exercise
This is the bottom number of your blood pressure. People with a high body weight are at risk for high blood pressure. Try to check your blood pressure often to and try to keep it in a healthy range with diet and exercise. This helps prevent other health conditions.
Apolipoprotein B (apoB) is the backbone of three lipoproteins (LDL, VLDL, and IDL) or particles that carry “bad cholesterol” in your blood. Lower apoB levels are associated with better heart health.
Homocysteine is an amino acid found in very small amounts in your body. Cognitive decline is associated with low homocysteine.
Homocysteine is an amino acid found in very small amounts in your body. That’s because our bodies convert it into vitamin B12, B9, or B6. Hence, higher homocysteine levels can signal a deficiency of these vitamins. Higher homocysteine levels may also be linked to brain disease.
Free testosterone is testosterone that is not bound to any proteins. It is made from cholesterol and is mainly produced by the testes in men or ovaries in women. Testing free testosterone levels may be necessary for men and women who have symptoms of low testosterone but have normal total testosterone levels.
High testosterone levels are associated with hair loss, especially in women. If your testosterone levels are high, talk to your doctor about further testing and treatment.
It is best to measure your testosterone 3 months after stopping birth control.
High DHEA sulfate levels are associated with hair loss, especially in women. If your DHEA sulfate levels are high, talk to your doctor about further testing and treatment.
Both omega-3 and omega-6 are important for your health. Lower omega-6:omega-3 ratios are considered healthier. Omega-3-rich diets may contribute to better working memory.
The omega-6/omega-3 ratio looks at the balance between omega-6s and omega-3s in your blood. It reflects your omega intake. It is normally used to assess whether or not you have an increased risk of heart disease and chronic low-grade inflammation.
ESR is a blood test that gives a sense of how much inflammation is occurring in your body. People with irritable bowel should be tested for ESR to exclude inflammatory bowel disease.
ESR is a blood test that gives a sense of how much inflammation is occurring in your body. Inflammation from viral infections, tissue damage or trauma, or other medical conditions can raise ESR.
Your total cholesterol is the total amount of good and bad cholesterol in your blood. Most of your total cholesterol is 'bad cholesterol,' or LDL-cholesterol. Higher total cholesterol may raise your risk of artery hardening
Your total cholesterol is the total amount of good and bad cholesterol in your blood. Most of your total cholesterol is 'bad cholesterol,' or LDL-cholesterol. Lower total cholesterol levels are associated with better heart health.
Your total cholesterol is the total amount of good and bad cholesterol in your blood. Most of your total cholesterol is 'bad cholesterol,' or LDL-cholesterol. Lower total cholesterol levels are associated with better heart health.
SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode strongly encourages those who use our service to consult and work with an experienced healthcare provider as our services are not to replace the relationship with a licensed doctor or regular medical screenings.
Have a DNA file?
High Blood Sugar
Anxiety
Gluten Sensitivity
Gut Inflammation
Blood Pressure
IBS
Mood
Insomnia
PTSD
Mood Swings
Overweight
Memory Performance
Sexual Dysfunction
PCOS
Psoriasis
Joint Pain
Attention/ADHD
Chronic Fatigue / Tiredness
Allergies
Asthma
Acne
Tinnitus
Eczema
Food Allergy
Vitamin B6
Vitamin E
Restless Leg Syndrome
Grinding Teeth
Vitamin A
Magnesium
Zinc
Heart Health
Migraines
(High) Cholesterol
Headache
Chronic Pain
Back pain
Shoulder & Neck Pain
Stress
Inflammation
Omega-3 needs
Salt Sensitivity
Endurance
Power performance
Strength
Exercise recovery
Brain Fog
Female Fertility
Longevity
Addiction
Erectile Dysfunction
Male Infertility
MTHFR
Joint Inflammation
GERD
Ulcers
Sleep Apnea
Periodontitis
Varicose Veins
H. pylori
Liver Health
Canker Sores
Gallstones
Kidney Health
Gout
Hair Loss (Male-Pattern Baldness)
Riboflavin
Urticaria
Rosacea
Carpal Tunnel Syndrome
Sinus Congestion
Cavities
Artery Hardening
Vertigo
Vitiligo
Myopia
Indigestion
Excessive Sweating
Testosterone – Males
Yeast infection (Candida)
Endometriosis
Tobacco addiction
Alcohol addiction
Uterine fibroids
Length of menstrual cycle
UTI
OCD
Kidney Stones
Vitamin B12
Vitamin C
Vitamin D
Folate
Iron
Eating Disorders
Bone Health
Hypothyroidism
Hyperthyroidism
Sugar Cravings
Hearing/difficulty problem /Hearing loss
Painful Periods
Palpitations
Hemorrhoids
Hypotension
Bladder Control
Constipation
Appendicitis
Low Blood Sugar
Irregular Periods
Metabolic rate
Visceral fat
Lung Health
Anemia
Calcium
Cognition
Cognitive Decline
Seasonal Low Mood
Vitamin K
Phosphate
HRV
Cluster headaches
Knee Pain
Hip Pain
Selenium
Low back injury
Dyslexia
Cannabis addiction
Histamine Intolerance
Carnitine
Pesticide Sensitivity
Organophosphate Sensitivity
Cadmium
Lead
Melatonin
FSH
T4
T3
High PTH
Potassium
Coenzyme Q10 (CoQ10)
Chromium
Oxalate Sensitivity
Salicylate Sensitivity
Facial Wrinkles
Age Spots
Ligament Rupture (ACL Injury)
Tendon Injury (Tendinopathy)
Omega 6
Omega 6:Omega 3 Ratio
Arachidonic Acid
Oleic Acid
Alpha-Linolenic Acid
EPA
GLA
Linoleic Acid
DHA
Insulin Resistance
Sperm Motility
Homocysteine
C difficile
Pneumonia
EBV Infection
Gastrointestinal Infection
Chronic Bronchitis
Copper
Skin Elasticity
Skin Hydration
Egg allergy
ApoB
GGT
TIBC
Bioavailable Testosterone (Male)
MPV
Chloride
Free T4
Processing Speed
Short-term memory
TMAO
Air pollution sensitivity
Heart Rate
VO2 Max
Flu
Hair graying
Caffeine-Related Sleep Problems
Groin Hernia
Stretch marks
Droopy Eyelids
Strep infection
Dry eyes
Carbohydrate Consumption
Peanut allergy
Heart rate recovery
Muscle recovery
Jaw Disorders
HPV Infection
Acute Bronchitis
Chlamydia
Genital Herpes
Pancreas inflammation
Executive Function
Pyroglutamic acid
Raynaud’s
Liver Scarring
Dandruff
Bioavailable Testosterone (Female)
Shrimp allergy
Haptoglobin
Milk allergy
Beta-Alanine
Taurine
LDL Particle Size
Diarrhea
Snoring
Uric acid
Phenylalanine
Leucine
Glutamine
Valine
Glycine
Alanine
Lysine
Arginine
Histidine
Tyrosine
Cortisol
DHEAS
Insulin
Prolactin
TSH
Lactate
Ketone Bodies
IL-17A (Th17 Dominance)
Creatine Kinase
Neutrophils
Basophils
Eosinophils
Ferritin
ALT
AST
MCV
Hematocrit
RDW
SHBG
Total Protein
Albumin
MCH
Sodium
MCHC
Alkaline Phosphatase
Monocytes
Ghrelin
IL10 (Th2)
IL-6 (Th2 and Th17)
Iodine
Chili Pepper sensitivity
COMT
DRD2 (Dopamine)
Lectin Sensitivity
Thiamine
Biotin
Mold Sensitivity (Foodborne)
Chronic Lyme
BDNF
Glyphosate sensitivity
BPA Sensitivity
Pregnenolone
Luteinizing Hormone (LH)
Growth Hormone
IgA
Molybdenum
Sensitivity to Dairy (IgG Casein)
Telomere Length
Serotonin (5HIAA)
Non-Celiac Gluten Sensitivity (IgG Gliadin)
Manganese
Klotho
Mold Sensitivity (Airborne)
Amylase
Lipase
Low Sperm Count
Tryptophan
Methionine
Glutamate
Proline
Blood Calcium
Hypertriglyceridemia
HDL Cholesterol
HbA1c
Hemoglobin
Total Cholesterol
LDL Cholesterol
IGF1
Fasting Glucose
Bilirubin (total)
White blood cell count
Red blood cell count
Platelets
eGFR
Creatinine
Estradiol
Neuroticism
Sleep Quality
Lactose Intolerance
Saturated fat
Optimal diet
Unsaturated fat
Achilles tendon injury
Deep sleep
Fat
Response to Stress
Leadership
Ankle injury
Creativity
Hoarding
Protein
Optimal Exercise
Knee Injury
Rotator cuff injury
Extraversion
Risk-Taking
Happiness
Daytime Sleepiness
Morningness
Time spent watching TV
Disliking cilantro
Alcohol Sensitivity
Response to Caffeine
Snacking
Weight Regain
Sleep movement
Wearing glasses or contacts
Educational Attainment
Bitter Taste Sensitivity
Agreeableness
Aggression
Conscientiousness
Openness to experience
Physical activity
Caffeine-Related Anxiety
Naps