The G (minor) allele is associated with:

  • G = Increased Lymphotoxin a/Œ≤, which increases sjogren's, anti-Ro/SSA and anti-La/SSB antibody-positive
  • This causes a 1.31x increased risk in non-Hodgkin lymphoma in 5 SNP haplo.


Parent Gene: TNF

Importance: 3
Less common allele: G = 39%
More common allele: A = 61%
My Genotype: Log In
Risk Allele: G
Significance: risk factor