[PMID 18317464] schizophrenia and bipolar disorder rs1538979 (P=0.016; odds ratio=2.73+/-95% confidence interval (CI) 1.42-5.27) and rs821577 (P=0.040; odds ratio=1.64+/-95% CI 1.23-2.19)


[PMID 21376542] The effects of DISC1 risk variants on brain activation in controls, patients with bipolar disorder and patients with schizophrenia

[PMID 15386212] Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder.

[PMID 19188535] Association of variants in DISC1 with psychosis-related traits in a large population cohort.

[PMID 19300510] The DISC1 pathway modulates expression of neurodevelopmental, synaptogenic and sensory perception genes.

[PMID 19414483] The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations.

rs821577

Parent Gene: DISC1

Importance: 1
Less common allele: T = 38%
More common allele: G = 62%
My Genotype: Log In