[type-2 diabetes 851 Chinese people of Han descent (397 diabetes and 454 controls).

rs8052394G was significantly associated with the incidence of type 2 diabetes

Subjects with GA and GG genotypes (n = 24) had lower hair mercury levels than did subjects with MT1A AA (n = 113) [R].

[PMID 18194558] A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples.

[PMID 21128001] Metallothionein-1 genotypes in the risk of oral squamous cell carcinoma.

[PMID 22233731] An investigation of modifying effects of metallothionein single-nucleotide polymorphisms on the association between mercury exposure and biomarker levels.




[PMID 23429061] Metallothionein 1A polymorphisms may influence urine uric acid and N-acetyl-beta-D-glucosaminidase (NAG) excretion in chronic lead-exposed workers

[PMID 22805858] Effects of metallothionein-1 genetic polymorphism and cigarette smoking on the development of hepatocellular carcinoma.


Parent Gene: MT1A

Importance: 2
Less common allele: G = 18%
More common allele: A = 82%
My Genotype: Log In