The minor (C) allele is associated with a greater positive affect towards exercising over the course of a training session [R].


[PMID 23251365] Genetic Variants in the Fat and Obesity Associated (FTO) Gene and Risk of Alzheimer's Disease

[PMID 23921993] The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study

[PMID 18335027] Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP.

[PMID 19322589] Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study.

[PMID 19478790] The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.

[PMID 21102551] Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.

[PMID 21317302] FTO polymorphisms are associated with adult body mass index (BMI) and colorectal adenomas in African-Americans.

[PMID 26726774] Gender-Dependent Association of FTO Polymorphisms with Body Mass Index in Mexicans.


Parent Gene: FTO

Importance: 4
Less common allele: T = 39%
More common allele: C = 61%
My Genotype: Log In
Risk Allele: C

Disease/Trait: Osteoarthritis

The C allele of rs8044769 is reported to be associated with Osteoarthritis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Osteoarthritis.