Within the FTO gene, many SNPs appear to be co-inherited. The SNP showing the strongest association with body weight (i.e. body mass index, BMI) is not rs8043757, although this SNP is one of co-inherited SNPs in the FTO gene region. For more information, refer to the FTO gene or the most studied of FTO SNPs, rs9930506. [PMID 17658951]

[PMID 18379722] Variations in the FTO gene are associated with severe obesity in the Japanese.

rs8043757

Parent Gene: FTO

Importance: 4
Less common allele: T = 32%
More common allele: A = 68%
My Genotype: Log In
Risk Allele: T, T, T

Disease/Trait: Leptin Measurement

The T allele of rs8043757 is reported to be associated with Leptin Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with circulating leptin levels.

Disease/Trait: Leptin Measurement

The T allele of rs8043757 is reported to be associated with Leptin Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with circulating leptin levels (men).