​​The Major “T” allele is associated with:

  • Greater amount of central fat, as well as a higher percentage of central fat (white females) [R].

  • Wider waist circumference (white females) [R].

Note: the T allele is the minor in some populations.

This SNP is associated with (unknown which alleles):

  • Reduced risk of metabolic syndrome (MS) (male) [R]
  • JAK2 is in charge of blood cell growth and development, and it is also involved in the immune system [R].


Parent Gene: JAK2

Importance: 2
Less common allele: C = 48%
More common allele: T = 52%
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