rs757343 is a SNP of the VDR gene. It is significantly associated with polycystic ovary syndrome (PCOS) risk [R]. 

The ''C'' allele was overtransmitted and the ''T'' allele was significantly undertransmitted from parents to affected children in Type 1 diabetes (T1D) (P = 0.032, P = 0.002, respectively) [R].

Greater serum vitamin D was related to increased risk of prostate cancer in ''T'' allele carriers only (P trend= 0.01) [R].

 Presence of the ''T'' allele is associated with a 74% increased risk of severe phenotype development of polycystic ovary syndrome (PCOS) (OR, 1.74) [R].
 

rs757343

Parent Gene: VDR

Importance: 2
Less common allele: T = 13%
More common allele: C = 87%
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