The Minor "A" allele is associated with:

  • Increased levels of LDLR protein and increased LDLR receptor function.
  • Increased receptor function causes lower levels of non-HDL cholesterol. This protects against coronary artery disease and heart disease (OR=.76).


Parent Gene: LDLR

Importance: 3
Less common allele: A = 0%
More common allele: G = 100%
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