The Minor "A" allele is associated with:

  • Increased levels of LDLR protein and increased LDLR receptor function.
  • Increased receptor function causes lower levels of non-HDL cholesterol. This protects against coronary artery disease and heart disease (OR=.76).

rs72658867

Parent Gene: LDLR

Importance: 3
Less common allele: A = 0%
More common allele: G = 100%
My Genotype: Log In