Mechanism:

GG has higher levels of Nrf2 protein.

The Major "G" allele is associated with:

  • Longer survival in people with a biliary duct tumor (R).
  • Decreased risk of age-related macular degeneration (OR 0.44) (R).

rs6726395

Parent Gene: NFE2L2

Importance: 3
Less common allele: A = 43%
More common allele: G = 57%
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