rs6679677 was significantly associated with Hypothyroidism (P-value 2.8·10(-13); OR=1.36) [R]. 

rs6679677 was adverse for both Type 1 diabetes (T1D) and  Rheumatoid arthritis (RA) [R]. The ''A'' allele was significantly associated with T1D risk (OR = 2.13; p = 0.00001) [RR1].

The minor allele ''A'' demonstrated a marginal association with juvenile idiopathic arthritis (JIA) (OR 1.28; p <0.07) [RR1].

 

 

 

 

rs6679677

Parent Gene: PHTF1, PTPN22, RSBN1

Importance: 5
Less common allele: A = 3%
More common allele: C = 97%
My Genotype: Log In
Risk Allele: A, A, A, A, A, C, A, A, A

Disease/Trait: Type I Diabetes Mellitus

The A allele of rs6679677 is reported to be associated with Type I Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 1 diabetes.

Disease/Trait: Rheumatoid Arthritis

The A allele of rs6679677 is reported to be associated with Rheumatoid Arthritis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Rheumatoid arthritis.

Disease/Trait: Type I Diabetes Mellitus

The A allele of rs6679677 is reported to be associated with Type I Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 1 diabetes.

Disease/Trait: Rheumatoid Arthritis

rs6679677 is associated with Rheumatoid Arthritis (R) . It is reported to increased association with Rheumatoid arthritis. No specific risk allele was identified in the study.

Disease/Trait: Type I Diabetes Mellitus

The A allele of rs6679677 is reported to be associated with Type I Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 1 diabetes.

Disease/Trait: Hypothyroidism

The A allele of rs6679677 is reported to be associated with Hypothyroidism (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Hypothyroidism.

Disease/Trait: Crohn's Disease

The C allele of rs6679677 is reported to be associated with Crohn's Disease (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Crohn's disease.

Disease/Trait: Psoriasis

The A allele of rs6679677 is reported to be associated with Psoriasis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Pediatric autoimmune diseases.

Disease/Trait: Celiac Disease

The A allele of rs6679677 is reported to be associated with Celiac Disease (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Pediatric autoimmune diseases.

Disease/Trait: Systemic Lupus Erythematosus

The A allele of rs6679677 is reported to be associated with Systemic Lupus Erythematosus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Pediatric autoimmune diseases.

Disease/Trait: Type I Diabetes Mellitus

The A allele of rs6679677 is reported to be associated with Type I Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Pediatric autoimmune diseases.

Disease/Trait: Crohn's Disease

The A allele of rs6679677 is reported to be associated with Crohn's Disease (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Pediatric autoimmune diseases.

Disease/Trait: Chronic Childhood Arthritis

The A allele of rs6679677 is reported to be associated with Chronic Childhood Arthritis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Pediatric autoimmune diseases.

Disease/Trait: Ulcerative Colitis

The A allele of rs6679677 is reported to be associated with Ulcerative Colitis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Pediatric autoimmune diseases.

Disease/Trait: Ankylosing Spondylitis

The A allele of rs6679677 is reported to be associated with Ankylosing Spondylitis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Pediatric autoimmune diseases.

Disease/Trait: Autoimmune Thyroid Disease

The A allele of rs6679677 is reported to be associated with Autoimmune Thyroid Disease (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Pediatric autoimmune diseases.

Disease/Trait: Common Variable Immunodeficiency

The A allele of rs6679677 is reported to be associated with Common Variable Immunodeficiency (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Pediatric autoimmune diseases.

Disease/Trait: Autoimmune Disease

The A allele of rs6679677 is reported to be associated with Autoimmune Disease (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Pediatric autoimmune diseases.

Disease/Trait: Systemic Lupus Erythematosus

The A allele of rs6679677 is reported to be associated with Systemic Lupus Erythematosus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Systemic lupus erythematosus.

Disease/Trait: Anti-Neutrophil Antibody Associated Vasculitis

The A allele of rs6679677 is reported to be associated with Anti-neutrophil Antibody Associated Vasculitis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Antineutrophil cytoplasmic antibody-associated vasculitis.