Subjects with this SNP (rs6675281) had significant alterations of grey matter volumes in prefrontal and temporal brain regions [R].

The ''C'' allele was significantly overtransmitted in Schizophrenia (SZ) cases [RR1R2R3].

The ''T'' allele was significantly associated with a positive Mood Disorder Questionnaire (MDQ)-score in Attention deficit hyperactivity disorder (ADHD) cases (OR = 1.44; P = 0.01) [R].




Parent Gene: DISC1

Importance: 2
Less common allele: T = 10%
More common allele: C = 90%
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