rs6583817 was associated with a decreased risk of late onset Alzheimer's disease (LOAD) (OR = 0.87, p = 0.03) [R].

rs6583817 (no reported alleles) is associated with increased post-mortem cerebellar insulin degrading enzyme (IDE) mRNA, decreased plasma β-amyloid (Aβ), and decreased risk for Alzheimer's disease (AD) [RR1]. 

 

rs6583817

Parent Gene: IDE

Importance: 2
Less common allele: T = 20%
More common allele: C = 80%
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