The risk allele ''G'' is significantly associated with late-onset Fuchs corneal dystrophy (FCD) (odds ratio, 4.2; P = 4.28 x 10⁻¹⁵) [R].

''G'' allele was significantly associated with Fuchs' endothelial corneal dystrophy (FECD). The odds ratio (OR) of each copy of the ''G'' allele for FECD was estimated to be 9.5 [R].



Parent Gene: TCF4

Importance: 4
Less common allele: G = 7%
More common allele: T = 93%
My Genotype: Log In
Risk Allele: G

Disease/Trait: Fuchs' Endothelial Dystrophy

The G allele of rs613872 is reported to be associated with Fuchs' Endothelial Dystrophy (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Fuchs's corneal dystrophy.