rs610604 is a SNP located in the TNFAIP3 gene, and is significantly associated with Psoriasis.

The ''G'' allele showed a good response to all TNF blockers (OR = 1.50, P(corr) = 0.050) and etanercept (OR = 1.64, P(corr) = 0.016) in psoriasis patients [R]. 

Nondiabetic patients with the ''GG'' genotype had 30-45% lower A20 gene expression and hence an increased risk for coronary artery disease (CAD) [R].

Both the ''G'' allele and the dominant model genotype (GG + GT) were associated with the risk of psoriasis vulgaris (PV) (OR = 1.53; P = 0.01 and OR = 1.68, P < 0.01, respectively) [R].  

rs610604

Parent Gene: TNFAIP3

Importance: 4
Less common allele: G = 39%
More common allele: T = 61%
My Genotype: Log In
Risk Allele: G, G, G

Disease/Trait: Psoriasis

The G allele of rs610604 is reported to be associated with Psoriasis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Psoriasis.

Disease/Trait: Psoriasis

rs610604 is associated with Psoriasis (R) . It is reported to increased association with Psoriasis. No specific risk allele was identified in the study.

Disease/Trait: Psoriasis Vulgaris

The G allele of rs610604 is reported to be associated with Psoriasis Vulgaris . Your genotype was not identified for this SNP so we are unable to comment on your association with Psoriasis vulgaris.

Disease/Trait: Psoriasis

The G allele of rs610604 is reported to be associated with Psoriasis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cutaneous psoriasis.

Disease/Trait: Cutaneous Psoriasis Measurement

The G allele of rs610604 is reported to be associated with Cutaneous Psoriasis Measurement . Your genotype was not identified for this SNP so we are unable to comment on your association with Cutaneous psoriasis.