Mechanism:

Decreased ability to repair or destory damaged DNA. (A) [R]

Normal ability to repair or destory damaged DNA. (G) [R]

The Minor allele “A” is associated with:

  • Significantly increases risk of developing breast and ovarian cancer (AA and AG). [R]

    • AG risk is less significant than the AA variant.

The Major allele “G” is associated with:

  • Normal risk of developing breast and ovarian cancer (GG). [R]

rs55770810

Parent Gene: BRCA1

Importance: 2
Less common allele: None = None
More common allele: None = None
My Genotype: Log In
Risk Allele: T
Significance: Pathogenic