rs532545 is a SNP located in the promoter region of the CDA gene. It is found to be associated with hand-foot syndrome (HFS) appearance.

Note: HFS is a side effect of some cancer treatments like chemotherapy. It causes redness, swelling, and pain on the palms of the hands and/or the soles of the feet.

The ''T'' allele was associated with a higher incidence of grade 3 hand-foot syndrome (HFS): the estimated OR was 2.02 (P = 0.039) [R].



Parent Gene: CDA

Importance: 2
Less common allele: T = 19%
More common allele: C = 81%
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