Homozygous carriers of the minor allele ''C''  had a 51% increased risk of colorectal adenoma recurrence compared with GG homozygotes (relative risk, 1.51) [R]. 

''G'' allele is associated with post-treatment pain after endodontic treatment among endodontic patients (P = .025) [R].



Parent Gene: PTGS2

Importance: 2
Less common allele: G = 8%
More common allele: C = 92%
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