The Minor "C" allele is associated with:
- obesity in patients using antipsychotics (Variant C allele) (R);
- a protective effect against weight gain of patients with schizophrenia being treated with olanzapine (R);
- metabolic syndrome in patients being treated with antipsychotics (R1,R2,R3);
- lower likelihood of smoking (R);
- Lower risk of developing ADHD (R);
Note: these studies are either contradicting each other, or the orientation is the issue.