Mechanism

Decreased ability to repair or destory damaged DNA (G). [R]

Normal ability to repair or destory damaged DNA (C). [R]

The Minor allele “T” is associated with:

  • Increased risk for developing breast cancer (GG and GA). [R]

  • Radiation exposure more significantly Increases risk for developing breast cancer (GG and GA). [R]

The Major allele “C” is associated with:

rs4986850

Parent Gene: BRCA1

Importance: 2
Less common allele: T = 3%
More common allele: C = 97%
My Genotype: Log In