The A (major) allele is associated with
- AA/AG had an increased immune response (increase in IL-4 levels) to measles vaccine.
G (minor) allele is associated with:
- Lower risk of heart attacks.
- Higher blood pH.
- 10X higher levels of certain bacteria.
- Worse asthma.
- Increased risk of septic shock (body attacks itself during infection).
- Increased risk of Gram-negative bacterial infections.