[PMID 19366906] BRCA1 Breast Cancer Risk Is Modified by CYP19 Polymorphisms in Ashkenazi Jews


[PMID 19438456] Gene-wide association study between the aromatase gene (CYP19A1) and female pattern hair loss


[PMID 19478482] Genetic variation of CYP19 (aromatase) gene influences age at onset of Alzheimer's disease in women


[PMID 20144226] rs4646(A) allele carriers with breast cancer being treated with letrozole are reported to do worse than rs4646(C;C) patients, based on a study of (only) 95 women.


[PMID 20960227] Genetic variation in the androgen estrogen conversion pathway in relation to breast cancer prognosticators


[PMID 22511967] Potential Role of Aromatase over Estrogen Receptor Gene Polymorphisms in Migraine Susceptibility: A Case Control Study from North India


[PMID 16412218] Multilocus analysis of SNP and metabolic data within a given pathway.


[PMID 18049890] Single nucleotide polymorphisms of the aromatase gene (CYP19A1), HER2/neu status, and prognosis in breast cancer patients.


[PMID 18199708] Haplotype analyses of CYP19A1 gene variants and breast cancer risk: results from the Shanghai Breast Cancer Study.


[PMID 18274619] Association study of aromatase gene (CYP19A1) in essential hypertension.


[PMID 18603647] Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response.


[PMID 18622258] Association of genetic polymorphisms in CYP19A1 and blood levels of sex hormones among postmenopausal Chinese women.


[PMID 18654799] Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease.


[PMID 18941913] Coffee intake, variants in genes involved in caffeine metabolism, and the risk of epithelial ovarian cancer.


[PMID 19015200] Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer.


[PMID 19064562] Genetic variation in CYP19A1 and risk of breast cancer and fibrocystic breast conditions among women in Shanghai, China.


[PMID 19152063] Polymorphisms in estrogen metabolism and estrogen pathway genes and the risk of miscarriage.


[PMID 19168589] Variants in hormone-related genes and the risk of biliary tract cancers and stones: a population-based study in China.


[PMID 19194457] Association between arterial stiffness and variations in oestrogen-related genes.


[PMID 19794821] Anastrozole Use in Early Stage Breast Cancer of Post-Menopausal Women.


[PMID 20819792] Association of CYP19 and ESR1 pleiotropic genes with human longevity .


[PMID 21269619] Epistasis between FSHR and CYP19A1 polymorphisms is associated with premature ovarian failure.


[PMID 22638611] Estrogen synthesis genes CYP19A1, HSD3B1, and HSD3B2 in hypertensive disorders of pregnancy.




[PMID 23129173] Plasma estrone sulfate concentrations and genetic variation at the CYP19A1 locus in postmenopausal women with early breast cancer treated with letrozole


[PMID 23700878] Research on aromatase gene (CYP19A1) polymorphisms as a predictor of endocrine therapy effectiveness in breast cancer


[PMID 24324964] CYP19 Genetic Polymorphism Haplotype AASA Is Associated with a Poor Prognosis in Premenopausal Women with Lymph Node-Negative, Hormone Receptor-Positive Breast Cancer


[PMID 23408108] Regulation of aromatase expression in breast cancer treated with anastrozole neoadjuvant therapy.


[PMID 23540392] Impact of aromatase genetic variation on hormone levels and global outcome after severe TBI.


[PMID 25793413] The CYP19 RS4646 Polymorphism IS Related to the Prognosis of Stage I-II and Operable Stage III Breast Cancer


[PMID 26379441] No associations between aromatase gene polymorphisms and breast cancer risk in Saudi patients


[PMID 26463708] Association of Variants in Candidate Genes with Lipid Profiles in Women with Early Breast Cancer on Adjuvant Aromatase Inhibitor Therapy

rs4646

Parent Gene: CYP19A1

Importance: 1
Less common allele: A = 34%
More common allele: C = 66%
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