- Higher levels of COMT . lower levels of dopamine. Lower levels of norepinephrine (CC)
- Medium COMT activity (CT)
- Lower COMT activity. Higher levels of dopamine. Higher levels of norepinephrine. (TT)
The Minor "T" allele is associated with:
- Boys with TT had worse cognitive performance when acutely exposed to mercury. (R)
- Higher risk of endometrial cancer [R].
The Major "C" allele is associated with:
- Higher risk of atherosclerosis in women [R].