rs4570625 is a SNP in the TPH2 gene. It is significantly associated with Anxiety symptoms.
''G'' allele polymorphisms were found to be associated with a reduction in the NGA (Nogo-anteriorization) in both healthy controls and Attention-deficit/hyperactivity disorder (ADHD) patients [R].
Among healthy individuals, ''T'' allele carriers were associated with significantly smaller volumes in bilateral amygdala and hippocampus and higher reward dependence than those with ''G'' allele homozygotes [R].
The ''T'' allele was significantly less frequent in the Panic Disorder (PD) patients [R].
''G'' allele was preferentially transferred to children and adolescents with obsessive-compulsive disorder (OCD) [R].