Mechanism

  • CC: Decreased ability to repair or destory damaged DNA. [R]
  • GG: Decreased ability to repair or destory damaged DNA. [R]
  • T: Normal ability to repair or destory damaged DNA. [R]

The Minor allele “C” is associated with:

  • Increased risk of developing breast and ovarian cancer (CC). [R]

The Minor allele “G” is associated with:

  • Potential increase risk for developing breast and ovarian cancers (GG). [R]

    • Because of rarity this SNP further studies have to be conducted to determine the full risk.

The Major allele “T” is associated with:

  • Normal risk of developing breast and ovarian cancer (TT and TC and TG). [R]

rs45553935

Parent Gene: BRCA1

Importance: 2
Less common allele: None = None
More common allele: None = None
My Genotype: Log In