Mechanism:

  • Rs4320932 (T to C) is a variation in an intron in the IGF-2 gene (not part of the final product).
  • This leads to lower amounts of IGF-2 being made. IGF-2 is involved in growth and repair of cells (R).

The Minor "C" allele is associated with (lower IGF-2):

  • Decreased risk of ovarian cancer (R).
  • Increased risk of ovarian cancer coming back (R).

The Major "T" allele is associated with:

  • Decreased risk of Schizophrenia (R).
  • Increased height (R).

rs4320932

Parent Gene: IGF2

Importance: 3
Less common allele: C = 27%
More common allele: T = 73%
My Genotype: Log In