The G (minor) allele is associated with:

  • 2.75 mg/dl decreased levels of LDL cholesterol (R).
  • Decreased risk of developing coronary artery disease (5% decrease) (R).

  • Increased cholestanol to cholesterol ratio (R).

 

 

 

rs4299376

Parent Gene: ABCG8

Importance: 5
Less common allele: G = 17%
More common allele: T = 83%
My Genotype: Log In
Risk Allele: G, G, G, G

Disease/Trait: Low Density Lipoprotein Cholesterol Measurement

The G allele of rs4299376 is reported to be associated with Low Density Lipoprotein Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with LDL cholesterol.

Disease/Trait: Total Cholesterol Measurement

The G allele of rs4299376 is reported to be associated with Total Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cholesterol, total.

Disease/Trait: Low Density Lipoprotein Cholesterol Measurement

The G allele of rs4299376 is reported to be associated with Low Density Lipoprotein Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with LDL cholesterol.

Disease/Trait: Total Cholesterol Measurement

The G allele of rs4299376 is reported to be associated with Total Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cholesterol, total.

Disease/Trait: Lipid Measurement

rs4299376 is associated with Lipid Measurement (R) . It is reported to have a 2.595 unit increase on Lipid metabolism phenotypes (LDL-C.assay, fasting). No specific risk allele was identified in the study.