The G (minor) allele is associated with:

  • Decreased risk of developing type 2 diabetes (R).
  • Increased total cholesterol levels (R).
  • Increased levels of LDL cholesterol (R).

The A (major) allele is associated with:

  • Increased levels of triglycerides (AA) (R).
  • Low levels of LDL cholesterol (AA) (R).
  • Increased risk of developing type 2 diabetes (AA).

rs4148211

Parent Gene: ABCG8

Importance: 3
Less common allele: G = 44%
More common allele: A = 56%
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