Mechanism

  • AA: Decreased ability to repair or destory damaged DNA. [R]
  • CC: Decreased ability to repair or destory damaged DNA. [R]
  • G: Normal ability to repair or destory damaged DNA. [R]

The Minor allele “A” is associated with:

  • Increased risk of developing breast and ovarian cancer (AA). [R]

The Minor allele “C” is associated with:

  • Increased risk of developing breast and ovarian cancer (CC). [R]

The Major allele “G” is associated with:

  • Normal risk of developing breast and ovarian cancer (GG and GA and GC). [R]

rs41293455

Parent Gene: BRCA1

Importance: 2
Less common allele: None = None
More common allele: None = None
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