Defines the CYP2C19 variant known as CYP2C19*8.

Carriers of the rs41291556(C) allele may have decreased activity and poor metabolizer (PM) phenotype. This variant is associated with a dramatic (approximately 90% and 70%) reduction in the metabolism of S-mephenytoin and tolbutamide in vitro.[Clopidogrel Efficacy


Parent Gene: CYP2C19

Importance: 1
Less common allele: C = 0%
More common allele: T = 100%
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