rs3861950 is a SNP of the TNFSF4 gene. It was associated with the risk of vulnerable plaques of the carotid artery in a Chinese population [R].

Note: Cholesterol can combine with fat, calcium, and other substances in the blood to form a ''plaque''. Plaque then slowly builds up and hardens in the arteries.

The ''CC'' genotype conferred susceptibility to cerebral infarction (CI) (Odds ration = 2.896), and it was associated with a significantly higher risk of ischemic stroke (Odds ration = 3.520, P = 0.003) [R]. 



Parent Gene: TNFSF4

Importance: 2
Less common allele: C = 42%
More common allele: T = 58%
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