rs3861950 is a SNP of the TNFSF4 gene. It was associated with the risk of vulnerable plaques of the carotid artery in a Chinese population [R].
Note: Cholesterol can combine with fat, calcium, and other substances in the blood to form a ''plaque''. Plaque then slowly builds up and hardens in the arteries.
The ''CC'' genotype conferred susceptibility to cerebral infarction (CI) (Odds ration = 2.896), and it was associated with a significantly higher risk of ischemic stroke (Odds ration = 3.520, P = 0.003) [R].