rs3850641 is a SNP in the TNFSF4 gene. It has been significantly associated with Myocardial infarction (MI).

''G'' allele could increase the susceptibility to breast cancer (P = 0.009662) [R].

''G'' allele is associated with lower serum high-density lipoprotein (HDL) cholesterol and apolipoprotein levels as compared to those of genotype AA [R].

The minor allele ''G'' was significantly more frequent in individuals with myocardial infarction than in controls [R].

The GG genotype was significantly associated with autoimmune thyroid diseases (AITDs). Moreover, the ''G'' allele was in strong association with hypothyroidism in Hashimoto's thyroiditis (HT) (p = 0.018) [R].

rs3850641

Parent Gene: TNFSF4

Importance: 2
Less common allele: G = 14%
More common allele: A = 86%
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