- Rs3741208 (A to G) is a variation in an intron in the IGF-2 gene (not part of the final product).
- The mutation leads to lower amounts of IGF-2 being made. IGF-2 is involved in growth and repair of cells (R).
The Minor "A" allele is associated with:
- Increased risk of developing type 1 Diabetes (R).
The Major "G" allele is associated with (lower IGF-1):