rs3737787 is a SNP in the TSTD1 gene. It may effect lipid traits.

Minor genotype AA was associated with a low carotid artery intima - media thickness (IMT) (p=0.038) [R]. 

''A'' allele has a significant association with papillary thyroid cancer (PTC) risk (GA+AA vs GG: OR = 1·55; P = 0·001) and allelic model (G vs A: OR = 1·35; P = 0·003) [R].

Significant association between the common ''G'' allele and triglycerides (TGs) was observed in males (Pmale=0.03) and between the rare ''A'' allele and TGs in females (Pfemale=0.05) [R1, R2].

''A'' allele is significantly associated with raised triglycerides (P = 0.002) [R1, R2].

Females heterozygous for the major allele ''G'' had a significant incidence of type 2 diabetes (T2D) when compared to those homozygous for the major allele [R].




Parent Gene: TSTD1

Importance: 2
Less common allele: A = 17%
More common allele: G = 83%
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