Mechanism

  • TT: Decreased ability to repair or destory damaged DNA. [R]
  • G: Normal ability to repair or destory damaged DNA. [R]

The Minor allele “T” is associated with:

  • Increased risk of developing breast cancer (TT). [R]

  • Increased risk of developing prostate cancer (TT). [R]

The Major allele “C” is associated with:

  • Normal risk of developing breast cancer (CC and CT). [R]

  • Normal risk of developing prostate cancer (CC and CT). [R]

rs3737559

Parent Gene: BRCA1

Importance: 2
Less common allele: T = 6%
More common allele: C = 94%
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