The C (minor) allele is associated with:

  • Increased risk of developing coronary heart disease (R).
  • Increased risk of anemia (R).
  • Increased risk of developing peripheral neuropathy due to exposure to thalidomide, a drug used to help treat multiple myeloma (R). Peripheral neuropathy causes weakness, numbness and pain in the extremities due to nerve damage. 

rs363717

Parent Gene: ABCA1

Importance: 2
Less common allele: C = 14%
More common allele: T = 86%
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