The “T” (minor) allele is associated with:

  • The TT genotype averages several Performance IQ points higher than the CT genotype, which averages several Performance IQ points higher than the CC genotype [R].

  • Risk  of developing Alzheimer’s disease (T) [R].

The “C” allele is associated with:

  • Hyperactivity difficulties and other implications leading to autism spectrum disorders (CT) [R].

This SNP is associated with (unknown alleles):

  • Variation between IQ levels, as this SNP affects regulation of the temporal lobe, leading to different levels of cognitive ability [R]  

  • Higher risk of ADHD [R].

rs363043

Parent Gene: SNAP25

Importance: 3
Less common allele: T = 23%
More common allele: C = 77%
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