23andMe blog schizophrenia

  • rs3131296(C) increased the odds of schizophrenia by 1.19x
  • rs12807809(T) increased the odds of schizophrenia by 1.15x
  • rs9960767(C) increased the odds of schizophrenia by 1.23 times.

[PMID 20673877] A study of ~2,500 Han Chinese patients with schizophrenia did find rs3131296 to be significantly associated in this population.

[PMID 18204098] Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

[PMID 19343178] Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size.

[PMID 23053058] Search for schizophrenia susceptibility variants at the HLA-DRB1 locus among a British population

[PMID 22005930] Genome-wide association study of Alzheimer's disease with psychotic symptoms.

[PMID 25142293] Association between the NOTCH4 gene rs3131296 polymorphism with schizophrenia risk in the Chinese Zhuang population and Chinese Han population


Parent Gene: NOTCH4

Importance: 4
Less common allele: T = 8%
More common allele: C = 92%
My Genotype: Log In
Risk Allele: G

Disease/Trait: Schizophrenia

The G allele of rs3131296 is reported to be associated with Schizophrenia (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Schizophrenia.