- Monoamine Oxidase A is a gene responsible for the breakdown of hormones such as dopamine, serotonin, and norepinephrine in the body. [R]
- GG= Normal levels of Monoamine Oxidase A (MAOA) gene in the body [R]
- G (major allele)= Normal levels of MAOA gene in the body.
- A (minor allele)= Possible decrease of MAOA gene in the body [R], and therefore higher neurotransmitters.
The Minor "A" allele is associated with:
- Increased risk of ADHD [R] and more symptoms of ADHD [R].
- Increased risk of Autism [R] [R].
- Emotional flatness and depression [R].
- Increased risk of Schizophrenia [R] (preliminary).
- The variation in an interaction between MAOA and FOXKP2 may cause a decrease in the speech and language abilities of those with the polymorphism [R].
The Major "G" allele is associated with: