• Monoamine Oxidase A is a gene responsible for the breakdown of hormones such as dopamine, serotonin, and norepinephrine in the body. [R]

Mechanism:

  • GG= Normal levels of Monoamine Oxidase A (MAOA) gene in the body [R]
  • G (major allele)= Normal levels of MAOA gene in the body.
  • A (minor allele)= Possible decrease of MAOA gene in the body [R], and therefore higher neurotransmitters.

The Minor "A" allele is associated with:

  • Increased risk of ADHD [R] and more symptoms of ADHD [R].
  • Increased risk of Autism [R] [R].
  • Emotional flatness and depression [R].
  • Increased risk of Schizophrenia [R] (preliminary).
  • The variation in an interaction between MAOA and FOXKP2 may cause a decrease in the speech and language abilities of those with the polymorphism [R].

The Major "G" allele is associated with:

  • Lower risk for Schizophrenia, Autism, and ADHD [R] [R] [R] [R].
  • Increased cancer survival rate and cancer prognosis [R].
  • Increased risk of heart damage during cardiac injury [R].

rs3027407

Parent Gene: MAOA

Importance: 3
Less common allele: A = 45%
More common allele: G = 55%
My Genotype: Log In