The T (minor) allele is associated with:

  • TT= higher VEGF protein levels which can promote the growth of cancer and other vascular diseases (R1,R2,R3).

The C (major) allele is associated with:

  • CC= Increased risk of vasoocclusive crisis in sickle cell disease (R).

rs3025020

Parent Gene: VEGFA

Importance: 3
Less common allele: T = 23%
More common allele: C = 77%
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