[PMID 19064562] increased risk of breast cancer with concurrent proliferative fibrocystic conditions

  • rs1004982(C) 2.19 (1.24-3.85)
  • rs28566535(C) 2.20 (1.27-3.82)
  • rs936306(T) 1.94 (1.13-3.30)
  • rs4775936(C) 1.95 (1.07-3.58)

[PMID 17507620] Polymorphisms in the CYP19A1 (aromatase) gene and endometrial cancer risk in Chinese women.

[PMID 17827443] Interaction of soy food and tea consumption with CYP19A1 genetic polymorphisms in the development of endometrial cancer.

[PMID 18199708] Haplotype analyses of CYP19A1 gene variants and breast cancer risk: results from the Shanghai Breast Cancer Study.

[PMID 18622258] Association of genetic polymorphisms in CYP19A1 and blood levels of sex hormones among postmenopausal Chinese women.

[PMID 18941913] Coffee intake, variants in genes involved in caffeine metabolism, and the risk of epithelial ovarian cancer.

[PMID 19015200] Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer.


Parent Gene: CYP19A1

Importance: 1
Less common allele: C = 30%
More common allele: A = 70%
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