rs28399433, also known as -47A>C, is a SNP in the CYP2A6 gene.

[PMID 19339270] Genetic Associations of 115 Polymorphisms with Cancers of the Upper Aerodigestive Tract across 10 European Countries: The ARCAGE Project.

[PMID 22046326] 'Smoking Genes': A Genetic Association Study

[PMID 19371316] CYP2B6 (c.516G-->T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients.

[PMID 19659438] CYP2B6 variants and plasma efavirenz concentrations during antiretroviral therapy in Port-au-Prince, Haiti.

[PMID 24080498] Pharmacogenetic associations with plasma efavirenz concentrations and clinical correlates in a retrospective cohort of Ghanaian HIV-infected patients


Parent Gene: CYP2A6

Importance: 1
Less common allele: C = 13%
More common allele: A = 87%
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