Associated with at least one "mortality outcome" in a study of ~10,000 individuals.[PMID 18263601] [PMID 19436291] C-reactive protein haplotype is associated with high PSA as a marker of metastatic prostate cancer but not with overall cancer risk

[PMID 19101671] Association between C-reactive protein gene haplotypes and C-reactive protein levels in Taiwanese: interaction with obesity

[PMID 20552244] Genetic polymorphism of the C-reactive protein (CRP) gene and a deep infection focus determine maximal serum CRP level in Staphylococcus aureus bacteremia

[PMID 21293934] Association of C-reactive Protein Gene Polymorphisms and Colorectal Cancer

[PMID 21413847] Polymorphism in the C-reactive protein (CRP) gene affects CRP levels in plasma and one early marker of atherosclerosis in men: The Health 2000 Survey

[PMID 22241816] Relationship between CRP Polymorphism and Cardiovascular Events in Chinese Peritoneal Dialysis Patients

[PMID 21831326] CRP gene variation affects early development of Alzheimer's disease-related plaques

[PMID 15897982] Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels.

[PMID 16723442] A prospective assessment of the Y402H variant in complement factor H, genetic variants in C-reactive protein, and risk of age-related macular degeneration.

[PMID 17900590] C-reactive protein gene variation and type 2 diabetes mellitus: a case-control study.

[PMID 18167554] C-reactive protein (CRP) gene polymorphisms, CRP levels, and risk of incident coronary heart disease in two nested case-control studies.

[PMID 18216863] Genetic determinants of basal C-reactive protein expression in Filipino systemic lupus erythematosus families.

[PMID 18394581] Bayesian meta-analysis of genetic association studies with different sets of markers.

[PMID 18499652] C-reactive protein genotypes associated with circulating C-reactive protein but not with angiographic coronary artery disease: the LURIC study.

[PMID 18704199] Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration.

[PMID 19095725] Relation of genetic variation in the gene coding for C-reactive protein with its plasma protein concentrations: findings from the Women's Health Initiative Observational Cohort.

[PMID 19262552] C-reactive protein polymorphisms and genetic susceptibility to ischemic stroke and hemorrhagic stroke in the Chinese Han population.

[PMID 19426506] C-Reactive protein gene variants are associated with postoperative C-reactive protein levels after coronary artery bypass surgery.

[PMID 19545442] Marked differences in CRP genotype frequencies between the Fulani and sympatric ethnic groups in Africa.

[PMID 19624831] Functional analysis of the C-reactive protein (CRP) gene -717A>G polymorphism associated with coronary heart disease.

[PMID 19946607] Association of a single nucleotide polymorphism in the C-reactive protein gene (-286) with susceptibility to Plasmodium falciparum malaria.

[PMID 21496483] Fatigued breast cancer survivors and gene polymorphisms in the inflammatory pathway.

[PMID 21773944] Lack of association between the genetic variations in the C-reactive protein gene and the risk of psoriasis among the Taiwanese.

[PMID 23940726] Two variants of the C-reactive protein gene are associated with risk of pre-eclampsia in an american Indian population

[PMID 25027406] C-reactive protein genetic polymorphisms increase susceptibility to HBV-related hepatocellular carcinoma in a Chinese population

[PMID 26550110] The role of gene variants of the inflammatory markers CRP and TNF-Πin cardiovascular heart disease: systematic review and meta-analysis


Parent Gene: CRP

Importance: 1
Less common allele: C = 22%
More common allele: T = 78%
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