[rs27048]], a SNP in the dopamine transporter SLC6A3 gene, has been associated with more severe symptoms upon alcohol withdrawal, such as seizures, in a study of 250 Caucasian alcohol-dependent patients. Two haplotypes appear to be tagged by this SNP and a neighbor, rs27072. [PMID 18070248]

Variations in the DAT1 gene may affect the inattentive subtype of ADHD.[PMID 20800641]


[PMID 16537431] A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample.

rs27048

Parent Gene: SLC6A3

Importance: 1
Less common allele: T = 32%
More common allele: C = 68%
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