The Minor "T" is associated with: 

  • Lower LXR protein production, especially TT.
  • 2.63X higher risk of developing Alzheimer's (when combined with a bad HO-1 SNP) (TT) (R).
  • Higher risk for Ulcerative Colitis (TT)(R).
  • Higher colorectal cancer risk (TT).

The Major "C" allele is associated with:

  • Increased risk of preeclampsia.
  • CC increased the risk by 2.05X of developing preeclampsia (TC increased the risk by 1.85X) (R).


Parent Gene: LXR

Importance: 3
Less common allele: T = 22%
More common allele: C = 78%
My Genotype: Log In