The Minor "T" is associated with:
- Lower LXR protein production, especially TT.
- 2.63X higher risk of developing Alzheimer's (when combined with a bad HO-1 SNP) (TT) (R).
- Higher risk for Ulcerative Colitis (TT)(R).
- Higher colorectal cancer risk (TT).
The Major "C" allele is associated with:
- Increased risk of preeclampsia.
- CC increased the risk by 2.05X of developing preeclampsia (TC increased the risk by 1.85X) (R).