rs2515641 is a SNP in the CYP2E1 gene.

The rs2515641(T) allele defines the CYP2E1_10463T>C(F421F) variant.

[PMID 16385451] A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

[PMID 18663376] Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene.

[PMID 19131562] Biomarkers of human exposure to acrylamide and relation to polymorphisms in metabolizing genes.

[PMID 23460870] Cytochrome P450 2E1 gene polymorphisms/haplotypes and anti-tuberculosis drug-induced hepatitis in a Chinese cohort

[PMID 24654912] Association studies of cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1) gene polymorphisms with acute rejection in kidney transplantation recipients


Parent Gene: CYP2E1

Importance: 1
Less common allele: T = 30%
More common allele: C = 70%
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