[PMID 22197427] PTPN22 and myasthenia gravis: replication in an Italian population and meta-analysis of literature data

[PMID 17000021] No independent role of the -1123 G>C and+2740 A>G variants in the association of PTPN22 with type 1 diabetes and juvenile idiopathic arthritis in two Caucasian populations.

[PMID 17934143] Further evidence of a primary, causal association of the PTPN22 620W variant with type 1 diabetes.

[PMID 18075792] PTPN22: its role in SLE and autoimmunity.

[PMID 18252225] On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants.

[PMID 18578611] Associations of protein tyrosine phosphatase nonreceptor 22 (PTPN22) gene polymorphisms with susceptibility to Graves' disease in a Japanese population.

[PMID 19180477] Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations.

[PMID 19956096] rs2476601 T allele (R620W) defines high-risk PTPN22 type I diabetes-associated haplotypes with preliminary evidence for an additional protective haplotype.

[PMID 19956101] Overview of the Rapid Response data.

[PMID 19956106] Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.

[PMID 20722033] The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1.

[PMID 21193990] A PTPN22 promoter polymorphism -1123G>C is associated with RA pathogenesis in Chinese.

[PMID 22396730] No association of PTPN22 polymorphisms with susceptibility to ocular Behcet's disease in two Chinese Han populations.

[PMID 23025987] Recipient PTPN22 -1123 C/C genotype predicts acute graft-versus-host disease after HLA fully matched unrelated bone marrow transplantation for hematologic malignancies.

[PMID 23456301] Association of PTPN22 gene (rs2488457) polymorphism with ulcerative colitis and high levels of PTPN22 mRNA in ulcerative colitis.

[PMID 25073032] Association Between a Gain-of-Function Variant of PTPN22 and Rejection in Liver Transplantation

[PMID 25781893] STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C Polymorphisms Influence the Risk of Developing Juvenile Idiopathic Arthritis in Han Chinese Patients


Parent Gene: PTPN22

Importance: 4
Less common allele: G = 25%
More common allele: C = 75%
My Genotype: Log In