The C (minor) allele is associated with:

  • CC= significantly lower daily doses of warfarin (by .8mg) than wild allele.
  • Warfarin increases PXR . CC might be lower PXR, since it won't metabolize warfarin quickly.

rs2472682

Parent Gene: PXR

Importance: 2
Less common allele: C = 45%
More common allele: A = 55%
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