rs2416806 increases susceptibility to Rheumatoid Arthritis 1.36 times for heterozygotes (CG) and 1.52 times for homozygotes (GG) [PMID 17880261] [PMID 17827388] Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma.

[PMID 18648537] A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2.


Parent Gene: TRAF1

Importance: 1
Less common allele: G = 30%
More common allele: C = 70%
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